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Expression, Clinical significance and correlation of survivin and p53 in breast cancer  期刊论文  

  • 编号:
    0cfbdc6a-ddd6-424b-8ca7-ec6afe19bda0
  • 作者:
    Wang, Yuqian[0](王玉倩)[1]Zhang, Haihong[1][2];Wang, Peng[2][3];Yu, Xianghui[3][2];Kong, Wei[4][2];Cong, Xianling[5](丛宪玲)[4]
  • 地址:

    [1]Jilin University, Research Center,Changchun,China

    [2]Jilin University,Changchun,China

    [3]Jilin University, College of Life Sciences,Changchun,China

    [4]Jilin University, China-Japan Union Hospital,Changchun,China

  • 语种:
    英文
  • 期刊:
    BioTechnology: An Indian Journal ISSN:0974-7435 2013 年 8 卷 11 期 (1511 - 1514)
  • 收录:
  • 关键词:
  • 摘要:

    Objective The aim of this study was to investigate the clinical significance and correlation between auto-antibodies to survivin and protein-expression to p53 in breast cancer. Methods Enzyme-linked immunosorbent assay (ELISA) was used to examine the level of auto-antibodies against survivin in the serum of 92 breast cancer patients. The expression of p53 was evaluated by SP immunohistochemical staining technique. Results The positive rates of survivin auto-ntibody and p53 protein-expression in breast cancer were 15% and 34.78%. Survivin antibody and p53 overexpression in patients are closely related with lymph node metastasis of breast cancer. Conclusion Combined detection of p53 expression and survivin auto-antibody are valuable to estimation of prognosis and treatment of breast cancer. ? 2013 Trade Science Inc. - INDIA.

  • 推荐引用方式
    GB/T 7714:
    Wang Yuqian/9235787900[0],Zhang Haihong/40762718100[1],Wang Peng/56313681200[2], et al. Expression, Clinical significance and correlation of survivin and p53 in breast cancer [J].BioTechnology: An Indian Journal,2013,8(11):1511-1514.
  • APA:
    Wang Yuqian/9235787900[0],Zhang Haihong/40762718100[1],Wang Peng/56313681200[2],Yu Xianghui/8440795100[3],&Cong Xianling/15831159900[5].(2013).Expression, Clinical significance and correlation of survivin and p53 in breast cancer .BioTechnology: An Indian Journal,8(11):1511-1514.
  • MLA:
    Wang Yuqian/9235787900[0], et al. "Expression, Clinical significance and correlation of survivin and p53 in breast cancer" .BioTechnology: An Indian Journal 8,11(2013):1511-1514.
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