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Obstructive sleep apnea syndrome is a risk factor of hypertension  期刊论文  

  • 编号:
    2bc048c5-1ecd-45fe-9df9-f880e990c4c0
  • 作者:
  • 语种:
    英文
  • 期刊:
    MINERVA MEDICA ISSN:0026-4806 2016 年 107 卷 5 期 (294 - 299) ; OCT
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  • 关键词:
  • 摘要:

    INTRODUCTION: Some studies investigated the association between obstructive sleep apnea syndrome (OSAS) and hypertension risk. However, the results remained inconclusive. Thus, we performed a meta-analysis to clarify the association of OSAS and hypertension risk.
    EVIDENCE ACQUISITION: Online electronic databases (PubMed and EMBASE) was searched. The strength of association between the OSAS and hypertension risk was assessed by calculating OR with 95% CI.
    EVIDENCE SYNTHESIS: A total of 6 articles with 20,637 patients on OSAS and hypertension risk met the study inclusion criteria, and were included in the meta-analysis. OSAS was associated with a significantly increased risk of hypertension (OR=1.41; 95%CI, 1.29-1.8855 I-2=20%). In the race subgroup analysis, Caucasians with OSAS had increased hypertension risk (OR=1.43; 95%CI, 1.29-1.59; I-2=20%). In the subgroup analysis according to gender, male OSAS patients were significantly associated with risk of hypertension (OR=1.59; 95%CI, 1.16-2.17; I-2=0%), while female OSAS patients were not significantly associated with risk of hypertension (OR=1.18; 95%CI, 0.80-1.73; I-2=0%). All of the different severities of OSAS patients had an increased hypertension risk (mild: OR=1.26; 95%CI, 1.17-1.35; I-2=45%; moderate: OR=1.50; 95%CI, 1.27-1.76;I-2=46%; severe: OR=1.47; 95%CI, 1.33-1.64;I-2=63%).
    CONCLUSIONS: In conclusion, this meta-analysis suggested that OSAS may be associated with hypertension risk.

  • 推荐引用方式
    GB/T 7714:
    Meng Fanbo,Ma Jianghong,Wang Wei, et al. Obstructive sleep apnea syndrome is a risk factor of hypertension [J].MINERVA MEDICA,2016,107(5):294-299.
  • APA:
    Meng Fanbo,Ma Jianghong,Wang Wei,Lin Baisong.(2016).Obstructive sleep apnea syndrome is a risk factor of hypertension .MINERVA MEDICA,107(5):294-299.
  • MLA:
    Meng Fanbo, et al. "Obstructive sleep apnea syndrome is a risk factor of hypertension" .MINERVA MEDICA 107,5(2016):294-299.
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