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BNP as a potential biomarker for cardiac damage of breast cancer after radiotherapy: a meta-analysis 期刊论文

编号：

33cc5a41-da40-4a15-bd02-919c5ca519b1
作者：

Zhang, Cheng(张城)#^[1,2,3,4,5]Shi, Dan(施丹)^[6]Yang, Ping(杨萍)*^[1,2,3,4,5]
语种：

英文
期刊：

MEDICINE ISSN：0025-7974 2019 年 98 卷 29 期 ; JUL
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关键词：

BNP breast cancer radiotherapy
摘要：

Background: To analyze whether BNP could be a potential biomarker for cardiac damage of breast cancer after radiotherapy.
Methods: PubMed, Web of Science, ProQuest and Medline were searched using the key words "breast cancer" ("breast tumor", "breast neoplasm", or "breast carcinoma"), "brain natriuretic peptide" (or BNP) and "radiotherapy" (or "radiation therapy"). Four articles were selected and analyzed using the STATA 12.0 software package. The standard mean difference (SMD) and its standard error for BNP were calculated to assess the relationship between BNP and radiotherapy for breast cancer patients.
Results: In total, 172 patients with breast cancer were identified. The pooled SMD was -0.233 (95% CI -1.113, -0.057). The pooled estimated SMD for all studies showed obvious significant difference (z=3.99, P=.000). There was no publication bias.
Conclusions: This meta-analysis suggested that BNP could be a biomarker of cardiac damage at high heart absorbed doses according to radiotherapy, especially for left breast cancer patients.
推荐引用方式
GB/T 7714：

Zhang Cheng,Shi Dan,Yang Ping, et al. BNP as a potential biomarker for cardiac damage of breast cancer after radiotherapy: a meta-analysis [J].MEDICINE,2019,98(29).
APA：

Zhang Cheng,Shi Dan,Yang Ping.(2019).BNP as a potential biomarker for cardiac damage of breast cancer after radiotherapy: a meta-analysis .MEDICINE,98(29).
MLA：

Zhang Cheng, et al. "BNP as a potential biomarker for cardiac damage of breast cancer after radiotherapy: a meta-analysis" .MEDICINE 98,29(2019).
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