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Volume-related efficiency of gadolinium polyoxometalates as MRI contrast agents 期刊论文

编号：

366cffec-647c-47f2-9b2d-4e230b3749e6
作者：

Kong Daliang(孔大亮)#^[1]Wei Bo(韦博)^[1]Zhou Shengyan(周生岩)^[1]Yang Haishan(杨海山)*^[1]Jiang Yang(姜洋)*^[1]
语种：

英文
期刊：

CHEMICAL RESEARCH IN CHINESE UNIVERSITIES ISSN：1005-9040 2013 年 29 卷 6 期 (1055 - 1058) ; DEC
收录：
关键词：

Magnetic resonance imaging(MRI) Contrast agent Polyoxometalate
摘要：

Two gadolinium polyoxometalates, KCs4[Gd(alpha-SiW11O39)]center dot 25H(2)O(POM-1) and K-13[Gd(beta (2)-SiW11O39)(2)]center dot 27H(2)O(POM-2), have been evaluated as the candidates of potential magnetic resonance imaging T (1)(longitudinal relaxation) contrast agents. Longitudinal relaxivities of POM-2 are much higher than those of POM-1 in pure water and protein solution, respectively. However, compared with POM-1, POM-2 interacts with protein more strongly through electrostatic interaction, which is comfirmed by the fluoresence quenching of human serum albumin(HSA) in solutions with different polyoxometalate concentrations. Meanwhile, POM-1 presentes much lower cytotoxicity in the cell viability tests.
推荐引用方式
GB/T 7714：

Kong Da-liang,Wei Bo,Zhou Sheng-yan, et al. Volume-related efficiency of gadolinium polyoxometalates as MRI contrast agents [J].CHEMICAL RESEARCH IN CHINESE UNIVERSITIES,2013,29(6):1055-1058.
APA：

Kong Da-liang,Wei Bo,Zhou Sheng-yan,Yang Hai-shan,&Jiang Yang.(2013).Volume-related efficiency of gadolinium polyoxometalates as MRI contrast agents .CHEMICAL RESEARCH IN CHINESE UNIVERSITIES,29(6):1055-1058.
MLA：

Kong Da-liang, et al. "Volume-related efficiency of gadolinium polyoxometalates as MRI contrast agents" .CHEMICAL RESEARCH IN CHINESE UNIVERSITIES 29,6(2013):1055-1058.
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