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Synthesis of Novel Fluorescein-Thiospirolactams Hg2+ Fluorescent Probes and Its Application in vivo  期刊论文  

  • 编号:
    3f1b059c-47ae-418e-8d78-b0054a3f70ef
  • 作者:
    Liu Dahai#[1]Zhang Xueyan(张雪岩)[3]Feng Yusha[2];Du Xianlong[2];Xue Longqi[2];Du Jianshi(杜建时)*[1]Zhang Guirong[3];Yang Qingbiao[2];Li Yaoxian[2];
  • 语种:
    中文
  • 期刊:
    CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE ISSN:0251-0790 2018 年 39 卷 7 期 (1412 - 1419) ; JUL 10
  • 收录:
  • 摘要:

    The aldehyde compounds such as p-hydroxybenzaldehyde, pyrrole formaldehyde and acetaldehyd were introduced into the fluorescein thiohydrazide via the Schiff base reaction, the resulting compounds of TFP3, TFP4 and TFP5 could detect mercury with high selectivity and sensitivity. In further study, it was found that when the 7.5 mu mol/L Hg(2+ )was added, the fluorescence enhancement of TFP3, TFP4 and TFP5 at 530 nm of fluorescence spectrum appeared more than 30 times and the detection limits were 7.22x10(-8), 1.03x10(7) and 1. 28x10(-8) mol/L, respectively. In addition, the cellular imaging experiment exhibited that the probe had good biocompatibility and low toxicity, and may have practical application in the biological system.

  • 推荐引用方式
    GB/T 7714:
    Liu Dahai,Zhang Xueyan,Feng Yusha, 等. Synthesis of Novel Fluorescein-Thiospirolactams Hg2+ Fluorescent Probes and Its Application in vivo [J].CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,2018,39(7):1412-1419.
  • APA:
    Liu Dahai,Zhang Xueyan,Feng Yusha,Du Xianlong,&Li Yaoxian.(2018).Synthesis of Novel Fluorescein-Thiospirolactams Hg2+ Fluorescent Probes and Its Application in vivo .CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,39(7):1412-1419.
  • MLA:
    Liu Dahai, et al. "Synthesis of Novel Fluorescein-Thiospirolactams Hg2+ Fluorescent Probes and Its Application in vivo" .CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE 39,7(2018):1412-1419.
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