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Two New Baccharane Glycosides from Seeds of Impatientis balsamina L. with in vitro Growth Inhibitory Activity in Human Cancer A375 Cells  期刊论文  

  • 编号:
    7ad8044b-2816-47a0-a22d-802371bb9fc6
  • 作者:
    Wu Qian#[1]Jim Yongri[1];Yao Hua(姚华)[2]Liu Ying[1];Li Peng[1];Li Xuwen(李绪文)*[1]
  • 语种:
    英文
  • 期刊:
    CHEMICAL RESEARCH IN CHINESE UNIVERSITIES ISSN:1005-9040 2017 年 33 卷 5 期 (753 - 757) ; OCT
  • 收录:
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  • 摘要:

    Two new baccharane-type glycosides(1 and 2), together with seven known baccharane-type glycosides (3-9) hosenkoside A, hosenkoside B, hosenkoside C, hosenkoside F, hosenkoside M, hosenkoside K and hosenkoside G were isolated from the dried seeds of Impatientis balsamina L. The new baccharane-type glycosides were identified as honsenkol A-3-O-beta-D-glucopyranosyl-26-O-beta-D-glucopyranosyl-28-O-beta-D-glucopyranosyl-O-beta-D-glucopyranosyl(1) and (3S,4R,17R,20S)-17-hydroxy-3-O-beta-D-xylopyranose(12)-beta-D-glucopyranosyl-26-O-beta-D-glucopyranosyl-28-O-beta-D-glucopyranosyl-21,24-epoxybaccharane(2), respectively, by spectroscopic methods, including NMR(1D and 2D), lR and HR-ESI-MS. Compounds 1 and 2 were evaluated for in vitro inhibitory activity against the cell lines. Compound 2 with a new baccharane skeleton had anti-hepatic fibrosis activity against A375 cells in bioassay results, which means the new compounds have potential value in antitumor applications.

  • 推荐引用方式
    GB/T 7714:
    Wu Qian,Jim Yongri,Yao Hua, et al. Two New Baccharane Glycosides from Seeds of Impatientis balsamina L. with in vitro Growth Inhibitory Activity in Human Cancer A375 Cells [J].CHEMICAL RESEARCH IN CHINESE UNIVERSITIES,2017,33(5):753-757.
  • APA:
    Wu Qian,Jim Yongri,Yao Hua,Liu Ying,&Li Xuwen.(2017).Two New Baccharane Glycosides from Seeds of Impatientis balsamina L. with in vitro Growth Inhibitory Activity in Human Cancer A375 Cells .CHEMICAL RESEARCH IN CHINESE UNIVERSITIES,33(5):753-757.
  • MLA:
    Wu Qian, et al. "Two New Baccharane Glycosides from Seeds of Impatientis balsamina L. with in vitro Growth Inhibitory Activity in Human Cancer A375 Cells" .CHEMICAL RESEARCH IN CHINESE UNIVERSITIES 33,5(2017):753-757.
  • 入库时间:
    12/13/2019 2:07:42 PM
  • 更新时间:
    12/13/2019 2:07:42 PM
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