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Application of the Hepatic Transit Time (HTT) in Evaluation of Portal Vein Pressure in Gastroesophageal Varices Patients  期刊论文  

  • 编号:
    b925a40a-0160-4b6e-bdd4-b2c813ec4411
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  • 语种:
    英文
  • 期刊:
    JOURNAL OF ULTRASOUND IN MEDICINE ISSN:0278-4297 2019 年 38 卷 9 期 (2305 - 2314) ; SEP
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  • 摘要:

    Objectives To analyze the clinical significance of using hepatic transit time (HTT) to evaluate portal vein pressure in gastroesophageal varices patients. Methods For the observation group, we enrolled 50 gastroesophageal varices patients who had received esophagogastric variceal embolization in our hospital between January 2015 and February 2018. Patients without liver disease populated the control group and were recruited during the same time period. All patients underwent contrast-enhanced sonography. In the observation group, free portal pressure (FPP) was detected during esophagogastric variceal embolization with ultrasound guidance. Differences in hepatic artery-hepatic vein transit time (HA-HVTT), portal vein-hepatic vein transit time (PV-HVTT), and parenchyma-hepatic vein transit time (PA-HVTT) were compared between groups. Correlations between HA-HVTT, PV-HVTT, PA-HVTT, and FPP in the observation group were analyzed using the Pearson coefficient and linear regression analysis. Results HA-HVTT (t = 5.078; P < .001), PV-HVTT (t = 12.163; P < .001), and PA-HVTT (t = 2.649; P = .009) within the observation group were significantly lower than those of the control group. The areas under the curve of HTT were 0.771 (HA-HVTT), 0.951 (PV-HVTT), and 0.652 (PA-HVTT), and the sensitivity and specificity of PV-HVTT at 7.99 seconds were 86.0% and 88.0%, respectively. The HA-HVTT (r = -0.799; P < .001), PV-HVTT (r = -0.554; P < .001), and PA-HVTT (r = -0.735; P < .001) negatively correlated to FPP in the observation group. Linear regression analysis showed y = -0.410x + 7.254 (HA-HVTT and FPP), y = -0.335x + 4.983 (PV-HVTT and FPP), and y = -0.566x + 4.997 (PA-HVTT and FPP) in the observation group. Conclusion Compared with the control patients, the HTT of patients with portal hypertension-esophagogastric varices was significantly shorter, and showed an inverse relationship with FPP.

  • 推荐引用方式
    GB/T 7714:
    Lin Yuan-Qiang,Jiang Bo,Li He-Qun, et al. Application of the Hepatic Transit Time (HTT) in Evaluation of Portal Vein Pressure in Gastroesophageal Varices Patients [J].JOURNAL OF ULTRASOUND IN MEDICINE,2019,38(9):2305-2314.
  • APA:
    Lin Yuan-Qiang,Jiang Bo,Li He-Qun,Jin Chun-Xiang,&Wang Hui.(2019).Application of the Hepatic Transit Time (HTT) in Evaluation of Portal Vein Pressure in Gastroesophageal Varices Patients .JOURNAL OF ULTRASOUND IN MEDICINE,38(9):2305-2314.
  • MLA:
    Lin Yuan-Qiang, et al. "Application of the Hepatic Transit Time (HTT) in Evaluation of Portal Vein Pressure in Gastroesophageal Varices Patients" .JOURNAL OF ULTRASOUND IN MEDICINE 38,9(2019):2305-2314.
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