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Annexin A2 Coordinates STAT3 to Regulate the Invasion and Migration of Colorectal Cancer Cells In Vitro 期刊论文

编号：

baa543ef-5e5c-4837-a86b-ccc4c10f908d
作者：

Xiu, Dianhui(修殿辉)#^[1]Liu, Lin(柳林)^[1]Qiao, Fengli(乔锋利)^[2]Yang, Haishan(杨海山)^[1]Cui, Lu(崔璐)*^[3]Liu, Guifeng(刘桂锋)*^[1]
语种：

英文
期刊：

GASTROENTEROLOGY RESEARCH AND PRACTICE ISSN：1687-6121 2016 年 2016 卷 ; 2016
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摘要：

The present study aimed to reveal the expression of STAT3 and Anxa 2 in CRC specimens and to investigate the effects of STAT3 and Anxa 2 signaling on the proliferation, invasion, and migration in CRC Caco-2 cells. Results demonstrated that both Anxa 2 and STAT3 were highly expressed in CRC specimens in both mRNA and protein levels, with or without phosphorylation (Tyrosine 23 in Anxa 2 and Tyrosine 705 in STAT3). And the upregulated Anxa 2 promoted the phosphorylation of STAT3 (Tyrosine 705) in CRC Caco-2 cells. The upregulated Anxa 2 promoted the proliferation, migration, and invasion of Caco-2 cells in vitro. Moreover, the STAT3 knockdown also repressed the proliferation, migration, and invasion of Caco-2 cells. In conclusion, the overexpressed Annexin A2 regulated the proliferation, invasion, and migration in CRC cells in an association with STAT3.
推荐引用方式
GB/T 7714：

Xiu Dianhui,Liu Lin,Qiao Fengli, et al. Annexin A2 Coordinates STAT3 to Regulate the Invasion and Migration of Colorectal Cancer Cells In Vitro [J].GASTROENTEROLOGY RESEARCH AND PRACTICE,2016,2016.
APA：

Xiu Dianhui,Liu Lin,Qiao Fengli,Yang Haishan,&Liu Guifeng.(2016).Annexin A2 Coordinates STAT3 to Regulate the Invasion and Migration of Colorectal Cancer Cells In Vitro .GASTROENTEROLOGY RESEARCH AND PRACTICE,2016.
MLA：

Xiu Dianhui, et al. "Annexin A2 Coordinates STAT3 to Regulate the Invasion and Migration of Colorectal Cancer Cells In Vitro" .GASTROENTEROLOGY RESEARCH AND PRACTICE 2016(2016).
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