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Endotracheal catheter equipped with functional cuff produces clinically relevant positive end expiratory pressure: a bench study 期刊论文

编号：

e540649b-0465-421c-8a23-f32e2c069e2a
作者：

Wang, Jingwen#^[1,2]Su, Zhenbo(苏振波)^[2,3]Oto, Jun^[2,4];Kacmarek, Robert M.^[2,5];Jiang, Yandong^[6];Liu, Shujie*^[2,7]
语种：

英文
期刊：

JOURNAL OF CLINICAL MONITORING AND COMPUTING ISSN：1387-1307 2019 年 33 卷 3 期 (419 - 429) ; JUN
收录：
关键词：

PEEP Ventilation Tracheal Lung model Endotracheal catheter
摘要：

Recently, we developed a novel endotracheal catheter with functional cuff (ECFC). Using such an ECFC and a regular ICU ventilator, we were able to generate clinically relevant tidal volume in a lung model and adult human sized animal. This ECFC allows co-axial ventilation without using a jet ventilator. The aim of this study was to determine if ECFC also could generate clinically relevant positive end expiratory pressure (PEEP). The experiment was conducted on a model lung and artificial trachea. Lung model respiratory mechanics were set to simulate those of an adult human being. The tip of the distal end of ECFC 14 or 19 Fr catheter was positioned in the artificial trachea 3cm above the carina. The proximal end of ECFC was connected to an ordinary ICU ventilator. With 14 Fr catheter at respiratory rate 10bpm, PEEP 0, 2.9, 8.2, 12.9cmH(2)O was generated at preset PEEP 0, 5, 10, 15cmH(2)O respectively and tidal volume was up to 393.4ml. With 19 Fr catheter, PEEP was 0, 2.8, 7.6, 12.3cmH(2)O, at preset PEEP 0, 5, 10, 15cmH(2)O respectively and the tidal volume was up to 667.3ml. With 14 Fr catheter at respiratory rate 20bpm, PEEP was 0, 3.9, 9.6, 14.6cmH(2)O at preset PEEP 0, 5, 10, 15cmH(2)O respectively and tidal volume was up to 188.8ml. With 19 Fr catheter, PEEP was 0, 3.6, 8.9, 13cmH(2)O, at preset PEEP 0, 5, 10, 15cmH(2)O respectively and tidal volume was up to 345.3ml. ECFC enables clinicians to generate not only adequate tidal volume but also clinically relevant PEEP via co-axial ventilation using an ordinary ICU ventilator.
推荐引用方式
GB/T 7714：

Wang Jingwen,Su Zhenbo,Oto Jun, et al. Endotracheal catheter equipped with functional cuff produces clinically relevant positive end expiratory pressure: a bench study [J].JOURNAL OF CLINICAL MONITORING AND COMPUTING,2019,33(3):419-429.
APA：

Wang Jingwen,Su Zhenbo,Oto Jun,Kacmarek Robert M.,&Liu Shujie.(2019).Endotracheal catheter equipped with functional cuff produces clinically relevant positive end expiratory pressure: a bench study .JOURNAL OF CLINICAL MONITORING AND COMPUTING,33(3):419-429.
MLA：

Wang Jingwen, et al. "Endotracheal catheter equipped with functional cuff produces clinically relevant positive end expiratory pressure: a bench study" .JOURNAL OF CLINICAL MONITORING AND COMPUTING 33,3(2019):419-429.
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